One precedent for this is the Nervos CKB VM, which is basically RISC-V.

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Polkadot, Nervos, and other blockchain networks have experimented with RISC-V virtual machines, creating real-world precedents that support Ethereum’s consideration of a similar transition.

Polkadot, Nervos, and other blockchain networks have experimented with RISC-V virtual machines, creating real-world precedents that support Ethereum’s consideration of a similar transition.